
AACR Special Conference in Cancer Research: Cancer Dormancy and Residual Disease
Recent literature underscores that the biology of minimal residual disease (MRD) and tumor dormancy is distinct from that of established metastasis. Key unanswered questions include how DCCs evolve clonally at distant sites, the epigenetic and transcriptional programs that enforce dormancy, the role of organ-specific niches and immune surveillance and immune evasion, and the mechanisms by which dormant cells evade therapy and eventually reactivate. This second AACR conference focused on these topics will bring together basic scientists, clinicians, technology developers, and translational researchers to help catalyze the development of new strategies for tracking, targeting, and ultimately eradicating dormant cancer cells – transforming the prospects for true metastasis prevention and long-term cancer survival. Make plans to join us in Toronto for this exciting conference.